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Terpenes Increase the Lipid Dynamics in the Leishmania Plasma Membrane at Concentrations Similar to Their IC(50) Values
Although many terpenes have shown antitumor, antibacterial, antifungal, and antiparasitic activity, the mechanism of action is not well established. Electron paramagnetic resonance (EPR) spectroscopy of the spin-labeled 5-doxyl stearic acid revealed remarkable fluidity increases in the plasma membra...
Autores principales: | Camargos, Heverton Silva, Moreira, Rodrigo Alves, Mendanha, Sebastião Antonio, Fernandes, Kelly Souza, Dorta, Miriam Leandro, Alonso, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125203/ https://www.ncbi.nlm.nih.gov/pubmed/25101672 http://dx.doi.org/10.1371/journal.pone.0104429 |
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