Improving the Anti-Toxin Abilities of the CMG2-Fc Fusion Protein with the Aid of Computational Design

CMG2-Fc is a fusion protein composed of the extracellular domain of capillary morphogenesis protein 2 (CMG2) and the Fc region of human immunoglobulin G; CMG2-Fc neutralizes anthrax toxin and offers protection against Bacillus anthracis challenge. To enhance the efficacy of CMG2-Fc against anthrax t...

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Detalles Bibliográficos
Autores principales: Xi, Yongyi, Wu, Xiaojie, Gao, Lihua, Shao, Yong, Peng, Hui, Chen, Hongxing, Chen, Huipeng, Hu, Xianwen, Yue, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125234/
https://www.ncbi.nlm.nih.gov/pubmed/25101992
http://dx.doi.org/10.1371/journal.pone.0104674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125234/
https://www.ncbi.nlm.nih.gov/pubmed/25101992
http://dx.doi.org/10.1371/journal.pone.0104674

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