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The Murine Gammaherpesvirus Immediate-Early Rta Synergizes with IRF4, Targeting Expression of the Viral M1 Superantigen to Plasma Cells
MHV68 is a murine gammaherpesvirus that infects laboratory mice and thus provides a tractable small animal model for characterizing critical aspects of gammaherpesvirus pathogenesis. Having evolved with their natural host, herpesviruses encode numerous gene products that are involved in modulating h...
Autores principales: | O'Flaherty, Brigid M., Soni, Tanushree, Wakeman, Brian S., Speck, Samuel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125235/ https://www.ncbi.nlm.nih.gov/pubmed/25101696 http://dx.doi.org/10.1371/journal.ppat.1004302 |
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