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A Co-CRISPR Strategy for Efficient Genome Editing in Caenorhabditis elegans

Genome editing based on CRISPR (clustered regularly interspaced short palindromic repeats)-associated nuclease (Cas9) has been successfully applied in dozens of diverse plant and animal species, including the nematode Caenorhabditis elegans. The rapid life cycle and easy access to the ovary by micro...

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Detalles Bibliográficos
Autores principales: Kim, Heesun, Ishidate, Takao, Ghanta, Krishna S., Seth, Meetu, Conte, Darryl, Shirayama, Masaki, Mello, Craig C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125384/
https://www.ncbi.nlm.nih.gov/pubmed/24879462
http://dx.doi.org/10.1534/genetics.114.166389