The Principal Role of Ku in Telomere Length Maintenance Is Promotion of Est1 Association with Telomeres

Telomere length is tightly regulated in cells that express telomerase. The Saccharomyces cerevisiae Ku heterodimer, a DNA end-binding complex, positively regulates telomere length in a telomerase-dependent manner. Ku associates with the telomerase RNA subunit TLC1, and this association is required f...

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Detalles Bibliográficos
Autores principales: Williams, Jaime M., Ouenzar, Faissal, Lemon, Laramie D., Chartrand, Pascal, Bertuch, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125388/
https://www.ncbi.nlm.nih.gov/pubmed/24879463
http://dx.doi.org/10.1534/genetics.114.164707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125388/
https://www.ncbi.nlm.nih.gov/pubmed/24879463
http://dx.doi.org/10.1534/genetics.114.164707

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