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A protein-RNA specificity code enables targeted activation of an endogenous human transcript
Programmable protein scaffolds that target DNA are invaluable tools for genome engineering and designer control of transcription. RNA manipulation provides broad new opportunities for control, including changes in translation. PUF proteins are an attractive platform for that purpose, as they bind sp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125476/ https://www.ncbi.nlm.nih.gov/pubmed/24997599 http://dx.doi.org/10.1038/nsmb.2847 |