Cargando…
A protein-RNA specificity code enables targeted activation of an endogenous human transcript
Programmable protein scaffolds that target DNA are invaluable tools for genome engineering and designer control of transcription. RNA manipulation provides broad new opportunities for control, including changes in translation. PUF proteins are an attractive platform for that purpose, as they bind sp...
Autores principales: | Campbell, Zachary T., Valley, Cary T., Wickens, Marvin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125476/ https://www.ncbi.nlm.nih.gov/pubmed/24997599 http://dx.doi.org/10.1038/nsmb.2847 |
Ejemplares similares
-
Direct RNA sequencing enables m(6)A detection in endogenous transcript isoforms at base-specific resolution
por: Lorenz, Daniel A., et al.
Publicado: (2020) -
Modular assembly of designer PUF proteins for specific post-transcriptional regulation of endogenous RNA
por: Abil, Zhanar, et al.
Publicado: (2014) -
Activation of an endogenous retrovirus-associated long non-coding RNA in human adenocarcinoma
por: Gibb, Ewan A, et al.
Publicado: (2015) -
Gene-specific quantification of nascent transcription following targeted degradation of endogenous proteins in cultured cells
por: Guarnaccia, Alissa D., et al.
Publicado: (2021) -
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq
por: Zhu, Jinhang, et al.
Publicado: (2016)