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Proteome analysis reveals roles of L-DOPA in response to oxidative stress in neurons

BACKGROUND: Parkinson’s disease (PD) is the second most common neurodegenerative movement disorder, caused by preferential dopaminergic neuronal cell death in the substantia nigra, a process also influenced by oxidative stress. L-3,4-dihydroxyphenylalanine (L-DOPA) represents the main treatment rout...

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Detalles Bibliográficos
Autores principales: Jami, Mohammad-Saeid, Pal, Ramavati, Hoedt, Esthelle, Neubert, Thomas A, Larsen, Jan Petter, Møller, Simon Geir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125692/
https://www.ncbi.nlm.nih.gov/pubmed/25082231
http://dx.doi.org/10.1186/1471-2202-15-93