The fatal alliance of cancer and T cells: How pancreatic tumor cells gather immunosuppressive T cells

Immune evasion is a hallmark of cancer. We recently identified the adhesion molecule L1CAM as biomarker of pancreatic ductal adenocarcinoma (PDAC) associated with poor prognosis. During inflammation-associated carcinogenesis, L1CAM drives the enrichment of highly immunosuppressive CD4(+)CD25(-)CD69(...

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Detalles Bibliográficos
Autores principales: Grage-Griebenow, Evelin, Schäfer, Heiner, Sebens, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126073/
https://www.ncbi.nlm.nih.gov/pubmed/25114835
http://dx.doi.org/10.4161/onci.29382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126073/
https://www.ncbi.nlm.nih.gov/pubmed/25114835
http://dx.doi.org/10.4161/onci.29382

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