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Crystal structure of the lytic CHAP(K) domain of the endolysin LysK from Staphylococcus aureus bacteriophage K

BACKGROUND: Bacteriophages encode endolysins to lyse their host cell and allow escape of their progeny. Endolysins are also active against Gram-positive bacteria when applied from the outside and are thus attractive anti-bacterial agents. LysK, an endolysin from staphylococcal phage K, contains an N...

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Detalles Bibliográficos
Autores principales: Sanz-Gaitero, Marta, Keary, Ruth, Garcia-Doval, Carmela, Coffey, Aidan, van Raaij, Mark J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126393/
https://www.ncbi.nlm.nih.gov/pubmed/25064136
http://dx.doi.org/10.1186/1743-422X-11-133