FISH comets show that the salvage enzyme TK1 contributes to gene-specific DNA repair

Thymidine kinase 1 (TK1) is a salvage enzyme that phosphorylates thymidine, imported from surrounding fluids, to create dTMP, which is further phosphorylated to the DNA precursor dTTP. TK1 deficiency has for a long time been known to cause increased cellular sensitivity to DNA damage. We have examin...

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Detalles Bibliográficos
Autores principales: McAllister, Katherine A., Yasseen, Akeel A., McKerr, George, Downes, C. S., McKelvey-Martin, Valerie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126492/
https://www.ncbi.nlm.nih.gov/pubmed/25152750
http://dx.doi.org/10.3389/fgene.2014.00233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126492/
https://www.ncbi.nlm.nih.gov/pubmed/25152750
http://dx.doi.org/10.3389/fgene.2014.00233

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