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Interfering with mineralocorticoid receptor activation: the past, present, and future

Aldosterone is a potent mineralocorticoid produced by the adrenal gland. Aldosterone binds to and activates the mineralocorticoid receptor (MR) in a plethora of tissues, but the cardiovascular actions of aldosterone are of primary interest clinically. Although MR antagonists were developed as antihy...

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Detalles Bibliográficos
Autor principal: Dorrance, Anne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126546/
https://www.ncbi.nlm.nih.gov/pubmed/25165560
http://dx.doi.org/10.12703/P6-61