MALT1 Auto-Proteolysis Is Essential for NF-κB-Dependent Gene Transcription in Activated Lymphocytes

Mucosa-associated lymphoid tissue 1 (MALT1) controls antigen receptor–mediated signalling to nuclear factor κB (NF-κB) through both its adaptor and protease function. Upon antigen stimulation, MALT1 forms a complex with BCL10 and CARMA1, which is essential for initial IκBα phosphorylation and NF-κB...

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Detalles Bibliográficos
Autores principales: Baens, Mathijs, Bonsignore, Luca, Somers, Riet, Vanderheydt, Charlotte, Weeks, Stephen D., Gunnarsson, Jenny, Nilsson, Ewa, Roth, Robert G., Thome, Margot, Marynen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126661/
https://www.ncbi.nlm.nih.gov/pubmed/25105596
http://dx.doi.org/10.1371/journal.pone.0103774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126661/
https://www.ncbi.nlm.nih.gov/pubmed/25105596
http://dx.doi.org/10.1371/journal.pone.0103774

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