Cargando…

The Impact of Pneumolysin on the Macrophage Response to Streptococcus pneumoniae is Strain-Dependent

Streptococcus pneumoniae is the world's leading cause of pneumonia, bacteremia, meningitis and otitis media. A major pneumococcal virulence factor is the cholesterol-dependent cytolysin, which has the defining property of forming pores in cholesterol-containing membranes. In recent times a clin...

Descripción completa

Detalles Bibliográficos
Autores principales: Harvey, Richard M., Hughes, Catherine E., Paton, Adrienne W., Trappetti, Claudia, Tweten, Rodney K., Paton, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126675/
https://www.ncbi.nlm.nih.gov/pubmed/25105894
http://dx.doi.org/10.1371/journal.pone.0103625