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The Impact of Pneumolysin on the Macrophage Response to Streptococcus pneumoniae is Strain-Dependent
Streptococcus pneumoniae is the world's leading cause of pneumonia, bacteremia, meningitis and otitis media. A major pneumococcal virulence factor is the cholesterol-dependent cytolysin, which has the defining property of forming pores in cholesterol-containing membranes. In recent times a clin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126675/ https://www.ncbi.nlm.nih.gov/pubmed/25105894 http://dx.doi.org/10.1371/journal.pone.0103625 |