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The Impact of Pneumolysin on the Macrophage Response to Streptococcus pneumoniae is Strain-Dependent

Streptococcus pneumoniae is the world's leading cause of pneumonia, bacteremia, meningitis and otitis media. A major pneumococcal virulence factor is the cholesterol-dependent cytolysin, which has the defining property of forming pores in cholesterol-containing membranes. In recent times a clin...

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Detalles Bibliográficos
Autores principales:	Harvey, Richard M., Hughes, Catherine E., Paton, Adrienne W., Trappetti, Claudia, Tweten, Rodney K., Paton, James C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126675/ https://www.ncbi.nlm.nih.gov/pubmed/25105894 http://dx.doi.org/10.1371/journal.pone.0103625

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