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Association of Liposome-Encapsulated Trivalent Antimonial with Ascorbic Acid: An Effective and Safe Strategy in the Treatment of Experimental Visceral Leishmaniasis

BACKGROUND: Visceral leishmaniasis (VL) is a chronic debilitating disease endemic in tropical and subtropical areas, caused by protozoan parasites of the genus Leishmania. Annually, it is estimated the occurrence of 0.2 to 0.4 million new cases of the disease worldwide. Considering the lack of an ef...

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Detalles Bibliográficos
Autores principales: Castro, Renata A. O., Silva-Barcellos, Neila M., Licio, Carolina S. A., Souza, Janine B., Souza-Testasicca, Míriam C., Ferreira, Flávia M., Batista, Mauricio A., Silveira-Lemos, Denise, Moura, Sandra L., Frézard, Frédéric, Rezende, Simone A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126701/
https://www.ncbi.nlm.nih.gov/pubmed/25105501
http://dx.doi.org/10.1371/journal.pone.0104055