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The Human Antiviral Factor TRIM11 Is under the Regulation of HIV-1 Vpr

TRIM11 has been reported to be able to restrict HIV-1 replication, but the detailed aspects of the interfering mechanisms remain unclear. In this study, we demonstrated that TRIM11 mainly suppressed the early steps of HIV-1 transduction, resulting in decreased reverse transcripts. Additionally, we f...

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Detalles Bibliográficos
Autores principales: Yuan, Ting, Yao, Weitong, Huang, Fang, Sun, Binlian, Yang, Rongge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126725/
https://www.ncbi.nlm.nih.gov/pubmed/25105968
http://dx.doi.org/10.1371/journal.pone.0104269