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The Human Antiviral Factor TRIM11 Is under the Regulation of HIV-1 Vpr
TRIM11 has been reported to be able to restrict HIV-1 replication, but the detailed aspects of the interfering mechanisms remain unclear. In this study, we demonstrated that TRIM11 mainly suppressed the early steps of HIV-1 transduction, resulting in decreased reverse transcripts. Additionally, we f...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126725/ https://www.ncbi.nlm.nih.gov/pubmed/25105968 http://dx.doi.org/10.1371/journal.pone.0104269 |