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Evaluation of Sexual Dimorphism in the Efficacy and Safety of Simvastatin/Atorvastatin Therapy in a Southern Brazilian Cohort

BACKGROUND: Dyslipidemia is the primary risk factor for cardiovascular disease, and statins have been effective in controlling lipid levels. Sex differences in the pharmacokinetics and pharmacodynamics of statins contribute to interindividual variations in drug efficacy and toxicity. OBJECTIVE: To e...

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Detalles Bibliográficos
Autores principales: Smiderle, Lisiane, Lima, Luciana O., Hutz, Mara Helena, der Sand, Cézar Roberto Van, der Sand, Luiz Carlos Van, Ferreira, Maria Elvira Wagner, Pires, Renan Canibal, Almeida, Silvana, Fiegenbaum, Marilu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126759/
https://www.ncbi.nlm.nih.gov/pubmed/25120083
http://dx.doi.org/10.5935/abc.20140085