Vacuolar protein sorting 35 (Vps35) rescues locomotor deficits and shortened lifespan in Drosophila expressing a Parkinson’s disease mutant of Leucine-rich repeat kinase 2 (LRRK2)

BACKGROUND: Parkinson’s disease (PD) is the most common movement neurodegenerative movement disorder. An incomplete understanding of the molecular pathways involved in its pathogenesis impedes the development of effective disease-modifying treatments. To address this gap, we have previously generate...

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Detalles Bibliográficos
Autores principales: Linhart, Radek, Wong, Sarah Anne, Cao, Jieyun, Tran, Melody, Huynh, Anne, Ardrey, Casey, Park, Jong Min, Hsu, Christine, Taha, Saher, Peterson, Rentia, Shea, Shannon, Kurian, Jason, Venderova, Katerina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126812/
https://www.ncbi.nlm.nih.gov/pubmed/24915984
http://dx.doi.org/10.1186/1750-1326-9-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126812/
https://www.ncbi.nlm.nih.gov/pubmed/24915984
http://dx.doi.org/10.1186/1750-1326-9-23

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