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SOX2 and cancer: current research and its implications in the clinic

SOX2 is a gene that encodes for a transcription factor belonging to the SOX gene family and contains a high-mobility group (HMG) domain, which permits highly specific DNA binding. Consequently, SOX2 functions as an activator or suppressor of gene transcription. SOX2 has been described as an essentia...

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Detalles Bibliográficos
Autores principales: Weina, Kasia, Utikal, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126816/
https://www.ncbi.nlm.nih.gov/pubmed/25114775
http://dx.doi.org/10.1186/2001-1326-3-19