STING-dependent cytosolic DNA sensor pathways regulate NKG2D ligand expression

The DNA damage response (DDR) upregulates the expression of NKG2D ligands (NKG2DLs).(1,2) We have recently reported that the DDR also induces the presence of cytosolic DNA in B-cell lymphoma cells, which leads to the activation of STING-dependent cytosolic DNA sensor pathways and the expression of R...

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Detalles Bibliográficos
Autores principales: Le Bert, Nina, Lam, Adeline R, Ho, Samantha SW, Shen, Yu J, Liu, Mo M, Gasser, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126837/
https://www.ncbi.nlm.nih.gov/pubmed/25114832
http://dx.doi.org/10.4161/onci.29259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126837/
https://www.ncbi.nlm.nih.gov/pubmed/25114832
http://dx.doi.org/10.4161/onci.29259

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