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Rapid Seeding of the Viral Reservoir Prior to SIV Viremia in Rhesus Monkeys

The viral reservoir represents a critical challenge facing HIV-1 eradication strategies(1–5). However, it remains unclear when and where the viral reservoir is seeded during acute infection and the extent to which it is susceptible to early antiretroviral therapy (ART). Here we show that the viral r...

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Detalles Bibliográficos
Autores principales: Whitney, James B., Hill, Alison L., Sanisetty, Srisowmya, Penaloza-MacMaster, Pablo, Liu, Jinyan, Shetty, Mayuri, Parenteau, Lily, Cabral, Crystal, Shields, Jennifer, Blackmore, Stephen, Smith, Jeffrey Y., Brinkman, Amanda L., Peter, Lauren E., Mathew, Sheeba I., Smith, Kaitlin M., Borducchi, Erica N., Rosenbloom, Daniel I.S., Lewis, Mark G., Hattersley, Jillian, Li, Bei, Hesselgesser, Joseph, Geleziunas, Romas, Robb, Merlin L., Kim, Jerome H., Michael, Nelson L., Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126858/
https://www.ncbi.nlm.nih.gov/pubmed/25042999
http://dx.doi.org/10.1038/nature13594