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Zampanolide and dactylolide: cytotoxic tubulin-assembly agents and promising anticancer leads

Covering: through January 2014 Zampanolide is a marine natural macrolide and a recent addition to the family of microtubule-stabilizing cytotoxic agents. Zampanolide exhibits unique effects on tubulin assembly and is more potent than paclitaxel against several multi-drug resistant cancer cell lines....

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Detalles Bibliográficos
Autores principales: Chen, Qiao-Hong, Kingston, David G. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126874/
https://www.ncbi.nlm.nih.gov/pubmed/24945566
http://dx.doi.org/10.1039/c4np00024b