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Protein Kinase D3 Is Essential for Prostratin-Activated Transcription of Integrated HIV-1 Provirus Promoter via NF-κB Signaling Pathway

Prostratin has been proposed as a promising reagent for eradicating the latent HIV-1 provirus by inducing HIV-1 transcription activation. The molecular mechanism of this activation, however, is far from clear. Here, we show that the protein kinase D3 (PKD3) is essential for prostratin-induced transc...

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Detalles Bibliográficos
Autores principales: Wang, Huiping, Zhu, Xinxing, Zhu, Ying, Liu, Jiangfang, Hu, Xiangming, Wang, Yu, Peng, Sijia, Chen, Yanheng, Chen, Ruichuan, Ding, Feng, Liu, Runzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127265/
https://www.ncbi.nlm.nih.gov/pubmed/25136641
http://dx.doi.org/10.1155/2014/968027