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Automated Synthesis of (18)F-Fluoropropoxytryptophan for Amino Acid Transporter System Imaging

Objective. This study was to develop a cGMP grade of [(18)F]fluoropropoxytryptophan ((18)F-FTP) to assess tryptophan transporters using an automated synthesizer. Methods. Tosylpropoxytryptophan (Ts-TP) was reacted with K(18)F/kryptofix complex. After column purification, solvent evaporation, and hyd...

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Detalles Bibliográficos
Autores principales: Shih, I-Hong, Duan, Xu-Dong, Kong, Fan-Lin, Williams, Michael D., Yang, Kevin, Zhang, Yin-Han, Yang, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127279/
https://www.ncbi.nlm.nih.gov/pubmed/25136592
http://dx.doi.org/10.1155/2014/492545