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Targeting α- and β-Adrenergic Receptors Differentially Shifts Th1, Th2, and Inflammatory Cytokine Profiles in Immune Organs to Attenuate Adjuvant Arthritis

The sympathetic nervous system (SNS) regulates host defense responses and restores homeostasis. SNS-immune regulation is altered in rheumatoid arthritis (RA) and rodent models of RA, characterized by nerve remodeling in immune organs and defective adrenergic receptor (AR) signaling to immune cell ta...

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Detalles Bibliográficos
Autores principales: Lubahn, Cheri L., Lorton, Dianne, Schaller, Jill A., Sweeney, Sarah J., Bellinger, Denise L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127464/
https://www.ncbi.nlm.nih.gov/pubmed/25157248
http://dx.doi.org/10.3389/fimmu.2014.00346