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Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells

Astrocytic endfeet cover the entire cerebral vasculature and serve as exchange sites for ions, metabolites, and energy substrates from the blood to the brain. They maintain endothelial tight junctions that form the blood-brain barrier (BBB) and release vasoactive molecules that regulate vascular ton...

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Detalles Bibliográficos
Autores principales: Watkins, Stacey, Robel, Stefanie, Kimbrough, Ian F., Robert, Stephanie M., Ellis-Davies, Graham, Sontheimer, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127490/
https://www.ncbi.nlm.nih.gov/pubmed/24943270
http://dx.doi.org/10.1038/ncomms5196