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Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells
Astrocytic endfeet cover the entire cerebral vasculature and serve as exchange sites for ions, metabolites, and energy substrates from the blood to the brain. They maintain endothelial tight junctions that form the blood-brain barrier (BBB) and release vasoactive molecules that regulate vascular ton...
Autores principales: | Watkins, Stacey, Robel, Stefanie, Kimbrough, Ian F., Robert, Stephanie M., Ellis-Davies, Graham, Sontheimer, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127490/ https://www.ncbi.nlm.nih.gov/pubmed/24943270 http://dx.doi.org/10.1038/ncomms5196 |
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