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miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesis

BACKGROUND: As a distinctive type of head and neck cancers, nasopharyngeal carcinoma (NPC) is genesis from the clonal Epstein-Barr virus (EBV)-infected nasopharyngeal epithelial cells accumulated with multiple genetic lesions. Among the recurrent genetic alterations defined, loss of 9p21.3 is the mo...

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Detalles Bibliográficos
Autores principales: Cheung, Chartia Ching-Mei, Chung, Grace Tin-Yun, Lun, Samantha Wei-Man, To, Ka-Fai, Choy, Kwong-Wai, Lau, Kin-Mang, Siu, Sharie Pui-Kei, Guan, Xin-Yuan, Ngan, Roger Kai-Cheong, Yip, Timothy Tak-Chun, Busson, Pierre, Tsao, Sai-Wah, Lo, Kwok-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127521/
https://www.ncbi.nlm.nih.gov/pubmed/25098679
http://dx.doi.org/10.1186/1476-4598-13-184