Aminoadamantanes with Persistent in Vitro Efficacy against H1N1 (2009) Influenza A

[Image: see text] A series of 2-adamantanamines with alkyl adducts of various lengths were examined for efficacy against strains of influenza A including those having an S31N mutation in M2 proton channel that confer resistance to amantadine and rimantadine. The addition of as little as one CH(2) gr...

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Detalles Bibliográficos
Autores principales: Kolocouris, Antonios, Tzitzoglaki, Christina, Johnson, F. Brent, Zell, Roland, Wright, Anna K., Cross, Timothy A., Tietjen, Ian, Fedida, David, Busath, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127532/
https://www.ncbi.nlm.nih.gov/pubmed/24793875
http://dx.doi.org/10.1021/jm500598u

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127532/
https://www.ncbi.nlm.nih.gov/pubmed/24793875
http://dx.doi.org/10.1021/jm500598u

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