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Aminoadamantanes with Persistent in Vitro Efficacy against H1N1 (2009) Influenza A
[Image: see text] A series of 2-adamantanamines with alkyl adducts of various lengths were examined for efficacy against strains of influenza A including those having an S31N mutation in M2 proton channel that confer resistance to amantadine and rimantadine. The addition of as little as one CH(2) gr...
Autores principales: | Kolocouris, Antonios, Tzitzoglaki, Christina, Johnson, F. Brent, Zell, Roland, Wright, Anna K., Cross, Timothy A., Tietjen, Ian, Fedida, David, Busath, David D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127532/ https://www.ncbi.nlm.nih.gov/pubmed/24793875 http://dx.doi.org/10.1021/jm500598u |
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