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Hypoxia augments the calcium-activated chloride current carried by anoctamin-1 in cardiac vascular endothelial cells of neonatal mice

BACKGROUND AND PURPOSE: The molecular identity of calcium-activated chloride channels (CaCCs) in vascular endothelial cells remains unknown. This study sought to identify whether anoctamin-1 (Ano1, also known as TMEM16A) functions as a CaCC and whether hypoxia alters the biophysical properties of An...

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Detalles Bibliográficos
Autores principales: Wu, Ming-Ming, Lou, Jie, Song, Bin-Lin, Gong, Yuan-Feng, Li, Yan-Chao, Yu, Chang-Jiang, Wang, Qiu-Shi, Ma, Tian-Xing, Ma, Ke, Hartzell, H Criss, Duan, Dayue Darrel, Zhao, Dan, Zhang, Zhi-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128065/
https://www.ncbi.nlm.nih.gov/pubmed/24758567
http://dx.doi.org/10.1111/bph.12730