Nonhomologous Recombination between Defective Poliovirus and Coxsackievirus Genomes Suggests a New Model of Genetic Plasticity for Picornaviruses

Most of the circulating vaccine-derived polioviruses (cVDPVs) implicated in poliomyelitis outbreaks in Madagascar have been shown to be recombinants between the type 2 poliovirus (PV) strain of the oral polio vaccine (Sabin 2) and another species C human enterovirus (HEV-C), such as type 17 coxsacki...

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Detalles Bibliográficos
Autores principales: Holmblat, Barbara, Jégouic, Sophie, Muslin, Claire, Blondel, Bruno, Joffret, Marie-Line, Delpeyroux, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128350/
https://www.ncbi.nlm.nih.gov/pubmed/25096874
http://dx.doi.org/10.1128/mBio.01119-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128350/
https://www.ncbi.nlm.nih.gov/pubmed/25096874
http://dx.doi.org/10.1128/mBio.01119-14

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