Host-Directed Antimicrobial Drugs with Broad-Spectrum Efficacy against Intracellular Bacterial Pathogens

We sought a new approach to treating infections by intracellular bacteria, namely, by altering host cell functions that support their growth. We screened a library of 640 Food and Drug Administration (FDA)-approved compounds for agents that render THP-1 cells resistant to infection by four intracell...

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Detalles Bibliográficos
Autores principales: Czyż, Daniel M., Potluri, Lakshmi-Prasad, Jain-Gupta, Neeta, Riley, Sean P., Martinez, Juan J., Steck, Theodore L., Crosson, Sean, Shuman, Howard A., Gabay, Joëlle E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128363/
https://www.ncbi.nlm.nih.gov/pubmed/25073644
http://dx.doi.org/10.1128/mBio.01534-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128363/
https://www.ncbi.nlm.nih.gov/pubmed/25073644
http://dx.doi.org/10.1128/mBio.01534-14

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