Cargando…

A20 deficiency causes spontaneous neuroinflammation in mice

BACKGROUND: A20 (TNFAIP3) is a pleiotropic NFκB-dependent gene that terminates NFκB activation in response to inflammatory stimuli. The potent anti-inflammatory properties of A20 are well characterized in several organs. However, little is known about its role in the brain. In this study, we investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Guedes, Renata Padilha, Csizmadia, Eva, Moll, Herwig P, Ma, Averil, Ferran, Christiane, da Silva, Cleide Gonçalves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128606/
https://www.ncbi.nlm.nih.gov/pubmed/25026958
http://dx.doi.org/10.1186/1742-2094-11-122