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A20 deficiency causes spontaneous neuroinflammation in mice

BACKGROUND: A20 (TNFAIP3) is a pleiotropic NFκB-dependent gene that terminates NFκB activation in response to inflammatory stimuli. The potent anti-inflammatory properties of A20 are well characterized in several organs. However, little is known about its role in the brain. In this study, we investi...

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Detalles Bibliográficos
Autores principales:	Guedes, Renata Padilha, Csizmadia, Eva, Moll, Herwig P, Ma, Averil, Ferran, Christiane, da Silva, Cleide Gonçalves
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128606/ https://www.ncbi.nlm.nih.gov/pubmed/25026958 http://dx.doi.org/10.1186/1742-2094-11-122

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