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Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline
BACKGROUND: Acute liver failure leads to systemic complications with one of the most dangerous being a decline in neurological function, termed hepatic encephalopathy. Neurological dysfunction is exacerbated by an increase of toxic metabolites in the brain that lead to neuroinflammation. Following v...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128607/ https://www.ncbi.nlm.nih.gov/pubmed/25012628 http://dx.doi.org/10.1186/1742-2094-11-121 |