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Role for Heat Shock Protein 90α in the Proliferation and Migration of HaCaT Cells and in the Deep Second-Degree Burn Wound Healing in Mice

Inflammation, proliferation, and tissue remodeling are essential steps for wound healing. The hypoxic wound microenvironment promotes cell migration through a hypoxia—heat shock protein 90 alpha (Hsp90α)—low density lipoprotein receptor-related protein-1 (LRP-1) autocrine loop. To elucidate the role...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Bai, Xiaozhi, Wang, Yunchuan, Li, Na, Li, Xiaoqiang, Han, Fei, Su, Linlin, Hu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128658/
https://www.ncbi.nlm.nih.gov/pubmed/25111496
http://dx.doi.org/10.1371/journal.pone.0103723