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AGR2, an Endoplasmic Reticulum Protein, Is Secreted into the Gastrointestinal Mucus
The MUC2 mucin is the major constituent of the two mucus layers in colon. Mice lacking the disulfide isomerase-like protein Agr2 have been shown to be more susceptible to colon inflammation. The Agr2(−/−) mice have less filled goblet cells and were now shown to have a poorly developed inner colon mu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128659/ https://www.ncbi.nlm.nih.gov/pubmed/25111734 http://dx.doi.org/10.1371/journal.pone.0104186 |