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Inhibition of CSF-1R Supports T-Cell Mediated Melanoma Therapy

Tumor associated macrophages (TAM) can promote angiogenesis, invasiveness and immunosuppression. The cytokine CSF-1 (or M-CSF) is an important factor of TAM recruitment and differentiation and several pharmacological agents targeting the CSF-1 receptor (CSF-1R) have been developed to regulate TAM in...

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Detalles Bibliográficos
Autores principales: Sluijter, Marjolein, van der Sluis, Tetje C., van der Velden, Pieter A., Versluis, Mieke, West, Brian L., van der Burg, Sjoerd H., van Hall, Thorbald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128661/
https://www.ncbi.nlm.nih.gov/pubmed/25110953
http://dx.doi.org/10.1371/journal.pone.0104230