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Theory on the Dynamics of Oscillatory Loops in the Transcription Factor Networks

We develop a detailed theoretical framework for various types of transcription factor gene oscillators. We further demonstrate that one can build genetic-oscillators which are tunable and robust against perturbations in the critical control parameters by coupling two or more independent Goodwin-Grif...

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Detalles Bibliográficos
Autor principal: Murugan, Rajamanickam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128676/
https://www.ncbi.nlm.nih.gov/pubmed/25111803
http://dx.doi.org/10.1371/journal.pone.0104328