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Palbociclib: an evidence-based review of its potential in the treatment of breast cancer

Cellular proliferation, growth, and division following DNA (deoxyribonucleic acid) damage are tightly controlled by the cell-cycle regulatory machinery. This machinery includes cyclin-dependent kinases (CDKs) which complex with their cyclin partners, allowing the cell cycle to progress. The cell-cyc...

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Detalles Bibliográficos
Autores principales: Cadoo, Karen A, Gucalp, Ayca, Traina, Tiffany A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128689/
https://www.ncbi.nlm.nih.gov/pubmed/25177151
http://dx.doi.org/10.2147/BCTT.S46725