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Characterization of Nodal/TGF-Lefty Signaling Pathway Gene Variants for Possible Roles in Congenital Heart Diseases

BACKGROUND: Nodal/TGF-Lefty signaling pathway has important effects at early stages of differentiation of human embryonic stem cells in directing them to differentiate into different embryonic lineages. LEFTY, one of transforming growth factors in the Nodal/TGF-Lefty signaling pathway, plays an impo...

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Detalles Bibliográficos
Autores principales: Deng, Xia, Zhou, Jing, Li, Fei-Feng, Yan, Peng, Zhao, Er-Ying, Hao, Ling, Yu, Kai-Jiang, Liu, Shu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128709/
https://www.ncbi.nlm.nih.gov/pubmed/25111179
http://dx.doi.org/10.1371/journal.pone.0104535