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Characterization of Nodal/TGF-Lefty Signaling Pathway Gene Variants for Possible Roles in Congenital Heart Diseases
BACKGROUND: Nodal/TGF-Lefty signaling pathway has important effects at early stages of differentiation of human embryonic stem cells in directing them to differentiate into different embryonic lineages. LEFTY, one of transforming growth factors in the Nodal/TGF-Lefty signaling pathway, plays an impo...
Autores principales: | Deng, Xia, Zhou, Jing, Li, Fei-Feng, Yan, Peng, Zhao, Er-Ying, Hao, Ling, Yu, Kai-Jiang, Liu, Shu-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128709/ https://www.ncbi.nlm.nih.gov/pubmed/25111179 http://dx.doi.org/10.1371/journal.pone.0104535 |
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