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Colorectal Cancers Mimic Structural Organization of Normal Colonic Crypts

Colonic crypts are stereotypical structures with distinct stem cell, proliferating, and differentiating compartments. Colorectal cancers derive from colonic crypt epithelia but, in contrast, form morphologically disarrayed glands. In this study, we investigated to which extent colorectal cancers phe...

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Detalles Bibliográficos
Autores principales: Cernat, Laura, Blaj, Cristina, Jackstadt, Rene, Brandl, Lydia, Engel, Jutta, Hermeking, Heiko, Jung, Andreas, Kirchner, Thomas, Horst, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128715/
https://www.ncbi.nlm.nih.gov/pubmed/25111606
http://dx.doi.org/10.1371/journal.pone.0104284