Design, synthesis, and anticancer activity of novel berberine derivatives prepared via CuAAC “click” chemistry as potential anticancer agents

A series of novel derivatives of phenyl-substituted berberine triazolyls has been designed and synthesized via copper-catalyzed azide-alkyne cycloaddition click chemistry in an attempt to develop antitumor agents. All of the compounds were evaluated for anticancer activity against a panel of three h...

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Detalles Bibliográficos
Autores principales: Jin, Xin, Yan, Tian-Hua, Yan, Lan, Li, Qian, Wang, Rui-Lian, Hu, Zhen-Lin, Jiang, Yuan-Ying, Sun, Qing-Yan, Cao, Yong-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128789/
https://www.ncbi.nlm.nih.gov/pubmed/25120353
http://dx.doi.org/10.2147/DDDT.S63228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128789/
https://www.ncbi.nlm.nih.gov/pubmed/25120353
http://dx.doi.org/10.2147/DDDT.S63228

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