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Can Gas Replace Protein Function? CO Abrogates the Oxidative Toxicity of Myoglobin

Outside their cellular environments, hemoglobin (Hb) and myoglobin (Mb) are known to wreak oxidative damage. Using haptoglobin (Hp) and hemopexin (Hx) the body defends itself against cell-free Hb, yet mechanisms of protection against oxidative harm from Mb are unclear. Mb may be implicated in oxidat...

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Detalles Bibliográficos
Autores principales: Sher, Elena A., Sholto, Alan Y., Shaklai, Mati, Shaklai, Nurith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128816/
https://www.ncbi.nlm.nih.gov/pubmed/25111140
http://dx.doi.org/10.1371/journal.pone.0104075