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Silencing B7-H1 enhances the anti-tumor effect of bladder cancer antigen-loaded dendritic cell vaccine in vitro

OBJECTIVE: The aim of this study was to examine whether short hairpin RNA (shRNA) expressing lentiviral particles targeting B7-H1 infection could result in B7-H1 knockdown on dendritic cells (DCs) and to investigate whether B7-H1 silencing could augment the immune function of DCs and further elicit...

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Detalles Bibliográficos
Autores principales: Wang, Shuo, Wang, Yonghua, Liu, Jing, Shao, Shixiu, Li, Xianjun, Gao, Jiannan, Niu, Haitao, Wang, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128850/
https://www.ncbi.nlm.nih.gov/pubmed/25120371
http://dx.doi.org/10.2147/OTT.S65367