Cargando…

BRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunction

BACKGROUND: BRAT1 (BRCA1-associated ATM activator 1) interacts with both BRCA1, ATM and DNA-PKcs, and has been implicated in DNA damage responses. However, based on our previous results, it has been shown that BRAT1 may be involved in cell growth and apoptosis, besides DNA damage responses, implying...

Descripción completa

Detalles Bibliográficos
Autores principales: So, Eui Young, Ouchi, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129107/
https://www.ncbi.nlm.nih.gov/pubmed/25070371
http://dx.doi.org/10.1186/1471-2407-14-548