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BRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunction
BACKGROUND: BRAT1 (BRCA1-associated ATM activator 1) interacts with both BRCA1, ATM and DNA-PKcs, and has been implicated in DNA damage responses. However, based on our previous results, it has been shown that BRAT1 may be involved in cell growth and apoptosis, besides DNA damage responses, implying...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4129107/ https://www.ncbi.nlm.nih.gov/pubmed/25070371 http://dx.doi.org/10.1186/1471-2407-14-548 |